Home

Cross-Reactive Arrays from the Anslyn Lab for Differential Sensing

Zoom link: https://utexas.zoom.us/j/95812751047 
YouTube Live link: https://youtube.com/live/wUXE0f9uWbs?feature=share 

Dr. Hazel Fragher
Department of Chemistry
University of Texas at Austin

ABSTRACT

Analyte detection using molecular probes remains paramount in many areas of scientific research and technology. Traditional analyte detection employs a “lock-and-key” principle in which a probe has highly complementary molecular recognition for an analyte. Although effective, this approach requires precise molecular design and can still suffer from non-specific detection, therefore evolution of practical molecular probes has historically been slow. In this talk, we will cover work from the Anslyn lab on differential sensing, an approach which uses machine learning to compare analyte responses to a broad array of crossreactive sensors and identify its unique fingerprint.

BIO

Hazel Fargher received her B.S. in Chemistry in 2016 from Worcester Polytechnic Institute. She received her Ph.D. in Physical Organic Chemistry in 2021 from the University of Oregon under the supervision of Profs. Darren Johnson and Michael Haley. During her thesis she studied host-guest chemistry with the hydro--chalcogenide anions. She is now a post-doctoral researcher in the Anslyn Labs atthe University of Texas at Austin where she studies information storage and retrieval in sequence-defined oligourethanes.